Genetic similarities between Spitz nevus and Spitzoid melanoma in children
نویسندگان
چکیده
منابع مشابه
Hypopigmented atypical Spitzoid neoplasms (atypical Spitz nevi, atypical Spitz tumors, Spitzoid melanoma): a clinicopathological update
The clinicopathologic classification, diagnosis, and management of Spitzoid melanocytic lesions is one of the most problematic topics in dermato-oncology and dermatopathology. After earlier anecdotal reports [1,2], the controversial history of these controversial lesions began in 1948 when Sophie Spitz described 13 cases of what she called “juvenile melanoma,” underlining its presumably good pr...
متن کاملAtypical Spitz Tumor of Uncertain Biologic Potential with Inopportune Localization in a 7-year-old Boy.
The Spitz nevus was first described as the “melanoma of childhood” or “juvenile melanoma” by Sophie Spitz in 1948 (1). Most spitzoid melanocytic proliferations can be classified as benign Spitz nevi or spitzoid melanomas based on published criteria (2-3). However, a subset of spitzoid lesions have histological features that deviate from a typical Spitz nevus, yet are insufficient for a definiti...
متن کاملSpitzoid melanoma.
Because spitzoid melanoma shares many histopathologic features with Spitz nevus, it is one of the most difficult lesions to diagnose in dermatopathology. Uncertainty exists in the medical literature about how to diagnose melanocytic proliferations including Spitz nevus and spitzoid melanoma. A misdiagnosis of a melanoma as Spitz nevus is one of the most frequent causes of malpractice lawsuits i...
متن کاملAngiomatoid Spitz Nevus.
Spitz nevus is a variant of melanocytic nevus which is histopathologically defined as large spindle and/or epithelioid cells. Angiomatoid Spitz nevus is a rare histologic variant of desmoplastic Spitz nevus characterized by prominent vasculature. We present a case of angiomatoid Spitz nevus, celluar type, that has not been reported before. We provide another example to show the remarkable diver...
متن کاملGenetic Analysis of Spitzoid Melanomas in Children
Melanoma is currently the sixth most common cancer in the United States with incidence rates increasing faster than for any other cancer. ii The lifetime risk of developing invasive melanoma in the United States is currently 1 in 71 compared with an estimate of 1 in 600 in 1960. However, despite these rising figures, melanoma of all types in childhood remains uncommon. Children represent 2% of ...
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ژورنال
عنوان ژورنال: Cancer
سال: 2004
ISSN: 0008-543X
DOI: 10.1002/cncr.20680